Search results for " Seroprevalence"

showing 8 items of 8 documents

Coxiella burnetii spread in Sicily

2015

Q fever is a zoonotic disease caused by C. burnetii. Common reservoirs of this worldwide disease are wild and domestic animals, especially sheep, goats, cattle. Q fever has been considered also an occupational disease for abattoir workers, sheep shearers, livestock farmers, and veterinarians due to their direct contact with potentially infected animals. The aims of this study were to estimate C. burnetii spread in Sicilian livestock and among rangers that live and work in Western Sicily. ELISA test on animal serum and IFI test on seasonal rangers sera were carried out. Real Time PCR was performed on milk and vaginal swab samples collected from animals to search for the C. burnetii DNA. The …

Settore MED/44 - Medicina Del LavoroCoxiella burnetii seroprevalence Real Time PCR
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Is Italian population protected from Poliovirus? Results of a seroprevalence survey in Florence, Italy

2018

ABSTRACT Objectives: Periodical assessments of population susceptibility to polioviruses (PV) is essential for evaluating population protection and planning appropriate vaccination strategies. The aim of the current work was to assess serological protective titers against all three polioviruses in the general population of Florence. Methods: A convenience sample of 328 sera, collected in 2009 in Florence (Central Italy) was analyzed. Samples were considered protective if neutralizing antibodies were detected at dilutions ≥1:8, according to the WHO protocols. Results: The immune coverage was 75.3%, 69.2% and 46% for PV1, PV2 and PV3, respectively. The protective titers of neutralizing antibo…

0301 basic medicineAdultMaleSettore MED/07 - Microbiologia E Microbiologia ClinicaIPV vaccine; Italy; OPV vaccine; poliomyelitis; seroprevalence.Adolescent030106 microbiologyPopulationpoliomyelitiImmunologymedicine.disease_causeAntibodies Viral03 medical and health sciencesYoung Adult0302 clinical medicineSeroepidemiologic StudiesEnvironmental healthSurveys and QuestionnairesmedicineSeroprevalenceImmunology and AllergyHumans030212 general & internal medicineeducationChildAgedPharmacologyAged 80 and overeducation.field_of_studyseroprevalencePoliovirusOPV vaccineInfant NewbornInfantMiddle Agedmedicine.diseaseItalian populationPoliomyelitisVaccinationIPV vaccinePoliovirusGeographyItalyChild PreschoolFemaleResearch PaperPoliomyelitisHuman Vaccines & Immunotherapeutics
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Free and antibody-complexed antigen and antibody profile in apparently healthy HIV seropositive individuals and in AIDS patients.

1990

The pattern of free and antibody-complexed HIV antigen and the antibody profile were investigated retrospectively in 305 serum samples taken from 22 AIDS patients before and during the development of AIDS and from 40 apparently healthy seropositive individuals. Most AIDS patients were found positive for both free and complexed antigen and had high gp41 antibody titres but low or undetectable p24 antibody. Four different patterns of HIV antigenaemia were observed: 1) positive for both free and complexed antigen; 2) negative for free HIV antigen at first, but always positive for complexed antigen; 3) positive for free antigen without complexed antigen; and 4) negative for both free and comple…

AdultMaleAntigen-Antibody ComplexHIV AntigensHIV Core Protein p24Gene Products gagAntigen-Antibody ComplexBiologyHIV AntibodiesVirusImmune systemAcquired immunodeficiency syndrome (AIDS)AntigenHIV SeroprevalenceVirologyHIV SeropositivitymedicineHumansSubstance Abuse IntravenousAcquired Immunodeficiency SyndromeViral Core Proteinsmedicine.diseaseVirologyImmune complexHIV Envelope Protein gp41Infectious DiseasesItalyImmunologybiology.proteinFemaleViral diseaseAntibodyBiomarkersJournal of medical virology
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The epidemiology of mumps in Italy.

2008

In Italy, although vaccination has been recommended for a number of years, vaccination coverage for mumps is still sub-optimal. The objective of the present study was to evaluate the seroprevalence of mumps antibodies in the Italian population, stratified by age, gender and geographical area. The proportion of individuals positive for mumps antibodies remained stable in the age classes 0–11 months and 1 year (25.4% and 30.8%, respectively) and showed a continuous increase after the second year of life. The percentage of susceptible individuals was higher than 20% in persons 2–14 years of age and exceeded 10% in persons 15–39 years of age. No statistically significant differences were observ…

AdultMalemedicine.medical_specialtySettore MED/07 - Microbiologia E Microbiologia ClinicaAdolescentDatabases FactualMumps; Seroprevalence; Vaccination; Adolescent; Adult; Age Factors; Child; Child Preschool; Databases Factual; Disease Outbreaks; Female; Humans; Immunoglobulin G; Infant; Italy; Male; Middle Aged; Mumps; Registries; Seroepidemiologic Studiesmumps; seroprevalence; vaccinationSerologyDisease OutbreaksDatabasesSeroepidemiologic StudiesEpidemiologymedicineSeroprevalenceHumansRegistriesPreschoolChildMumpsFactualGeneral VeterinaryGeneral Immunology and Microbiologyseroprevalencebusiness.industryPublic Health Environmental and Occupational HealthAge FactorsInfantMiddle AgedvaccinationItalian populationVirologyVaccinationMumps Seroprevalence VaccinationInfectious DiseasesItalyVaccination coverageChild PreschoolImmunoglobulin GMolecular MedicineFemaleViral diseasebusinessDemographyVaccine
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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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Seroprevalence of Borrelia burgdorferi in Stray Dogs from Southern Italy

2020

Borrelia burgdorferi is a bacterial pathogen transmitted by Ixodes ticks and is responsible for Lyme disease in both humans and dogs. The aim of this work was to evaluate B. burgdorferi diffusion among stray dogs in Palermo (Sicily, Italy) by serological methods in order to study the risk factors associated with the infection. Serum and blood samples of 316 dogs were collected from a shelter in Palermo, and were analyzed for the presence of antibodies against B. burgdorferi by indirect immunofluorescence assay (IFA), and of the ospA gene by real-time PCR, respectively. Seventeen sera (5.4%) were positive for the antibodies via IFA and one blood (0.3%) for ospA via real time PCR. On the basi…

0301 basic medicineMicrobiology (medical)030231 tropical medicineBiologySettore BIO/19 - Microbiologia GeneraleMicrobiologySerology03 medical and health sciences0302 clinical medicineLyme diseaseVirologymedicineSeroprevalenceBorrelia burgdorferilcsh:QH301-705.5PathogenseroprevalenceCommunicationospA gene<i>ospA</i> geneBorrelia burgdorferi seroprevalence030108 mycology & parasitologymedicine.diseasebiology.organism_classificationbacterial infections and mycosesVirologyBreed<i>Borrelia burgdorferi</i>lcsh:Biology (General)Borrelia burgdorferibiology.proteinIxodesAntibodystray dogsIFAMicroorganisms
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Has VZV epidemiology changed in Italy? Results of a seroprevalence study

2017

The aim of the study was to evaluate if and how varicella prevalence has changed in Italy. In particular a seroprevalence study was performed, comparing it to similar surveys conducted in pre-immunization era. During 2013–2014, sera obtained from blood samples taken for diagnostic purposes or routine investigations were collected in collaboration with at least one laboratory/center for each region, following the approval of the Ethics Committee. Data were stratified by sex and age. All samples were processed in a national reference laboratory by an immunoassay with high sensitivity and specificity. Statutory notifications, national hospital discharge database and mortality data related to V…

Male0301 basic medicinePediatricsCross-sectional studySeroprevalenceSettore MED/42 - Igiene Generale E ApplicataAntibodies Viralmedicine.disease_causeChickenpox0302 clinical medicineChickenpox; Immunization; Seroprevalence; Surveillance; Varicella-Zoster Virus; Adolescent; Adult; Age Factors; Aged; Aged 80 and over; Antibodies Viral; Chickenpox; Child; Child Preschool; Cross-Sectional Studies; Female; Humans; Infant; Infant Newborn; Italy; Male; Middle Aged; Seroepidemiologic Studies; Young Adult; Immunology and Allergy; Immunology; PharmacologySeroepidemiologic StudiesEpidemiology80 and overImmunology and AllergyAge FactorViral030212 general & internal medicineYoung adultChildskin and connective tissue diseasesAged 80 and overSurveillanceChickenpoxVaricella-Zoster ViruAge FactorsMiddle AgedResearch PapersItalyChild PreschoolFemaleChickenpox; Immunization; Seroprevalence; Surveillance; Varicella-Zoster Virus; Immunology and Allergy; Immunology; PharmacologyHumanAdultmedicine.medical_specialtyAdolescent030106 microbiologyImmunologyAntibodiesNOYoung Adult03 medical and health sciencesChickenpox; Immunization; Seroprevalence; Surveillance; Varicella-Zoster VirusmedicineHumansSeroprevalencePreschoolAgedCross-Sectional StudiePharmacologybusiness.industrySeroepidemiologic StudieInfant NewbornVaricella zoster virusInfantSeroepidemiologic StudiesNewbornmedicine.diseaseVaricella-Zoster VirusCross-Sectional StudiesImmunizationImmunizationsense organsChickenpox Immunization Seroprevalence Surveillance Varicella-Zoster Virus Immunology and Allergy Immunology Pharmacologybusiness
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Socio-economic and other correlates of Kaposi sarcoma-associated herpesvirus seroprevalence among older adults in Sicily.

2009

The virus that causes Kaposi sarcoma, KS-associated herpesvirus (KSHV, also known as human herpesvirus 8) has an unusual distribution and poorly characterized modes of transmission. To clarify these issues, socio-demographic correlates of KSHV seroprevalence were examined in a population-based study. In 1,154 randomly sampled adults (aged 32- 92, mean 71 years) throughout Sicily, KSHV antibodies were detected with four assays and a conservative algorithm. Seroprevalence was re-weighted to the population. Odds ratios with 95% confidence intervals (OR, CI) from multivariate logistic regression were used to estimate associations of seroprevalence with interview data. KSHV seroprevalence was 8.…

AdultMalemedicine.medical_specialtyPopulationLogistic regressionAntibodies ViralSettore MED/42 - Igiene Generale E ApplicataArticleSerologyRisk FactorsSeroepidemiologic StudiesVirologyEpidemiologymedicineSeroprevalenceGammaherpesvirinaeHumanseducationSicilyAgedAged 80 and overeducation.field_of_studybiologybusiness.industryOdds ratioHerpesviridae InfectionsMiddle Agedbiology.organism_classificationVirologyKSHV seroprevalence socio-economic correlates elderly SicilyConfidence intervalInfectious DiseasesSocioeconomic FactorsHerpesvirus 8 HumanFemalebusiness
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